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I recognized the connection between gout and sleep apnea about 15 years later when my sleep apnea was finally diagnosed and resolved and my frequent bouts of gout ended permanently. Men are at a higher risk than women. Pin On Health Sleep apnea happens when your muscles and soft tissues in your throat relax. Sleep apnea gout connection . While sleep apnea can lead to a series of potentially life threatening conditions including heart disease high blood pressure kidney disease liver conditions and stroke. However a study in the uk found that osa patients even with healthy bmi rates are twice as likely to develop gout as their peers who do not have sleep apnea. Physiologic support for my observation comes from pulmonology journal literature dating back more than 20 years which describes 2 physiologic mechanisms by which hypoxemia from sleep apnea can lead to gout flares. Observational studies have shown that people with sleep apnea have a higher prevalence of excess uric aci...